Profhilo® Structura: The Treatment Designed to Support Ageing Facial Fat

When most people think about facial ageing, they think about fine lines, wrinkles, and sagging skin. But one of the biggest changes that occurs with age actually happens deeper beneath the surface.

Facial fat changes.

Over time, the face naturally loses volume in some areas while gaining heaviness in others. This shift in facial structure is one of the key reasons the face can begin to look tired, hollow, heavy, and less defined — even before wrinkles become particularly noticeable.

This is where Profhilo Structura represents a completely different approach to facial rejuvenation. Rather than simply adding filler volume, Profhilo® Structura is designed to support and regenerate the superficial fat compartments of the face — helping restore structure, lift, and contour naturally.

In simple terms: it focuses on rebuilding facial support rather than just filling lines.

Why does the face change with age?

The ageing process affects multiple layers of the face simultaneously. These changes include loss of collagen and elastin, thinning of the skin, bone resorption, fat loss, and fat redistribution. Unfortunately, the face does not simply "age evenly."

Fat loss

Areas such as the cheeks, temples, and under-eye region often lose volume over time. This can create hollowing, shadows, a sunken appearance, and reduced facial support.

Fat descent and heaviness

At the same time, facial fat can also shift downward due to gravity and tissue laxity. This often contributes to jowls, heaviness in the lower face, loss of jawline definition, and facial sagging. Essentially, the face slowly begins redistributing itself in ways nobody particularly requested.

The role of collagen and skin quality

Alongside these structural changes, the skin itself also becomes thinner, less elastic, and less firm. As collagen and elastin production decline, the skin loses its ability to remain tight against the underlying structures — contributing to fine lines, wrinkles, loose skin, and deepening folds including nasolabial folds and marionette lines.

Bone loss also contributes to ageing

Ageing affects not only the skin and fat but also the facial skeleton itself. Over time, gradual bone resorption occurs in areas such as the jawline, cheeks, and around the eyes — reducing structural support for the overlying tissue and further contributing to hollowing, sagging, and changes in facial proportions. Which explains why ageing is far more complex than simply "getting wrinkles."

What is Profhilo® Structura?

Profhilo Structura is an advanced injectable treatment developed to address facial volume loss, tissue laxity, and structural ageing changes. Like traditional Profhilo, it uses hyaluronic acid (HA) — however, Structura is specifically designed to work deeper within the tissues to support facial fat compartments, structural support, and facial contour, rather than simply improving skin hydration alone.

How is Profhilo® Structura different from filler?

Traditional dermal fillers are designed primarily to add volume, sculpt contours, and replace lost structure. Profhilo Structura works differently. Instead of creating obvious volume, it helps stimulate regeneration and repositioning of superficial fat tissue using NAHYCO® Hybrid Technology — a unique formulation combining different molecular weights of hyaluronic acid to encourage tissue remodelling, fat pad support, improved structural integrity, and natural lifting effects.

The result is subtle, natural rejuvenation rather than a "filled" appearance. Because ideally people notice that you look fresher — not that your cheeks have suddenly acquired architectural ambition.

What are the benefits of Profhilo® Structura?

Restoration of facial support

Profhilo® Structura helps address midface volume loss, hollowing, facial flattening, and structural ageing — improving facial balance and support naturally.

Improved contour and lift

By supporting superficial fat pads, the treatment can help improve facial definition, mild sagging, jawline softness, and midface descent.

Natural-looking rejuvenation

The results are generally soft, subtle, and natural — without the appearance of excessive filler volume. Clinical studies have shown high patient satisfaction, with improvements continuing to develop over time following treatment. Because regeneration tends to look far more believable than instant overcorrection.

Understanding "sinkers" and "saggers"

One of the interesting concepts in facial ageing is that people often age in very different ways — broadly described as "sinkers" and "saggers." Profhilo Structura can help address both patterns.

Who is Profhilo® Structura suitable for?

This treatment may be suitable for patients experiencing midface volume loss, skin laxity, facial heaviness, early signs of structural ageing, or weight-loss related facial changes. It is often ideal for patients who want natural rejuvenation and subtle results, prefer not to have traditional filler volume, and want to improve facial support and contour. Treatment plans are tailored individually depending on facial anatomy, ageing pattern, skin quality, and desired outcome — because no two faces age in exactly the same way.

Profhilo® vs Profhilo® Structura

Although the names are similar, the purpose of the two treatments differs significantly:

	Profhilo®	Profhilo® Structura
Primary focus	Skin quality & hydration	Structural support & contour
Works within	The dermis	Subcutaneous tissue & fat compartments
Best for	Hydration, glow, fine lines, texture	Volume loss, midface ageing, tissue laxity
Adds volume?	No	Subtle structural support only
Depth of action	Superficial	Deeper structural layers

One improves the skin itself. The other supports the underlying structure beneath it.